Exercise on GLP-1: Workouts & Performance Protocol
Exercise accelerates weight loss 20-30% on GLP-1. But timing, intensity, and nutrition matter critically. This guide shows the evidence-based approach used by our Lagos fitness clients.
The Timeline: When to Start Training
Your body is adjusting to appetite suppression. Energy is lower. Side effects (nausea, fatigue) peak. Intense exercise = dangerous. Only activity: light 15-20 minute walks on days 3-5.
Appetite settling. Nausea fading. Energy returning. Start regular walking: 20-30 minutes daily, moderate pace (conversation pace). No strength training yet. Walking burns calories without depleting glycogen stores.
Side effects mostly gone. Appetite suppression stable. Energy normal. Now introduce structured strength + cardio. Phase approach below.
Why wait 4 weeks? Premature intense exercise on GLP-1 causes: severe nausea, fainting, dehydration. Your muscles need energy. GLP-1 reduces it. Give 4 weeks adaptation.
Phase 1 Exercise (Weeks 5-8): Foundation Building
Goal: Build habit, create calorie deficit, preserve muscle base
Frequency: 3-4 days/week
Structure: Strength training focus (body prefers preserving strength).
• Bodyweight squats: 3x 15 reps
• Lunges: 3x 10 each leg
• Calf raises: 3x 20
• Glute bridges: 3x 15
Duration: 30 minutes | Intensity: moderate | Rest 90 seconds between sets
• Push-ups: 3x 8-12 reps (or incline if needed)
• Rows (band or machine): 3x 12
• Dumbbell press: 3x 10
• Planks: 3x 30-45 seconds
Duration: 30 minutes | Intensity: moderate | Rest 90 seconds between sets
• Walking: 30-45 minutes OR light jogging: 20-30 minutes
• Keep heart rate 120-140 bpm (conversational pace)
• Duration: 30-45 minutes | Intensity: Low-moderate
Calorie burn estimate: 300-450 kcal total daily activity. Synergizes with appetite suppression for 1.0-1.2 kg/week loss.
Phase 2 Exercise (Weeks 9-16): Performance Building
Goal: Increase intensity, maintain muscle, accelerate weight loss
Frequency: 4-5 days/week
Progression: Add weights. Increase reps. Higher intensity cardio.
• Goblet squats: 4x 12 (5-8kg weight)
• Walking lunges: 3x 12 each leg
• Deadlifts (light): 3x 8 (10-15kg)
• Planks: 3x 60 seconds
• Russian twists: 3x 15 each side
Duration: 40 minutes | Rest: 60 seconds between sets
• Dumbbell bench press: 4x 10
• Bent rows: 4x 12
• Shoulder press: 3x 10
• Bicep curls: 3x 12
• Tricep dips: 3x 10
Duration: 40 minutes | Rest: 60 seconds between sets
• Option 1: Running 30-40 minutes (steady pace)
• Option 2: Interval training 25-30 min (3 min easy, 2 min moderate, repeat 5x)
• Cycling 40-50 minutes steady
Duration: 30-50 minutes | Intensity: Moderate-High
Calorie burn estimate: 500-700 kcal daily. Combined with GLP-1 = 1.2-1.5 kg/week loss.
Phase 3 Exercise (Weeks 17+): Maintenance & Optimization
Goal: Maintain muscle, optimize performance, reach target weight
Frequency: 5-6 days/week
Structure: Advanced strength + performance cardio
- Strength training: 4 days/week with progressive overload (add weight weekly)
- Cardio: 2 days/week (one steady, one interval-based)
- Rest: 1 day completely off
Key Exercise Principles on GLP-1
Principle 1: Prioritize Strength Over Cardio
Cardio burns calories but muscle training preserves lean mass. On GLP-1, you want:
- Maintain muscle (strength training most important)
- Burn extra calories (cardio secondary)
- Ratio: 60% strength, 40% cardio = best body composition
Principle 2: Eat Protein Post-Workout
Within 2 hours after strength training, consume 30-40g protein. Muscles need it for recovery. Appetite suppression might limit intake - use protein shake if needed.
Principle 3: Stay Hydrated During Exercise
GLP-1 causes dehydration risk. Drink 500-750mL water during workout. Don't wait until thirsty - thirst signal is suppressed.
Principle 4: Avoid Overtraining
Calorie deficit + exercise = recovery stress. Limit intense workouts to 3-4/week. Too much = fatigue, injury, weight loss plateau.
Exercise Mistakes to Avoid
Mistake 1: Starting intense exercise week 1-2 → Nausea/fainting risk. Wait until week 5 minimum.
Mistake 2: Doing only cardio → Lose muscle along with fat. Bad body composition. Add strength training.
Mistake 3: Not eating enough post-workout → Recovery impaired. Muscle breakdown. Worse results. Eat protein after training.
Mistake 4: Skipping rest days → Burnout. Injury. Illness. Muscle grows on rest, not training. Rest is critical.
Lagos Gym Recommendations
Equipment needed: Dumbbells (5-20kg), barbells, benches, pull-up bar. Any proper gym has these. Boutique CrossFit boxes also good for community/accountability.
Home workout alternative: If gym access is limited, bodyweight + resistance bands can cover most movements. Resistance bands are widely available online and in sports stores.
Popular Lagos gyms optimized for weight loss clients:
- Badgerfit - Multiple locations, good equipment, supportive community
- GymXperience - VI location, modern equipment
- Sweat Studios - Classes + strength, accountability factor
Tracking Exercise Progress
Record these weekly:
- Workouts completed: Did you hit your target 3-4 sessions?
- Weight/reps progression: Can you do more reps or use heavier weight?
- Energy during workout: 1-10 scale. Should improve week-to-week.
- Recovery quality: How sore next day? (Some soreness = training worked. Excessive = overtraining)
- Body measurements: Monthly waist/hip. Should decrease 1-2cm/week.
Special Scenarios
If Fatigued During Workout
Stop. Go home. Eat carbs + protein. Fatigue signals underfueling. Your body needs calories. GLP-1 suppresses hunger, not actual need for fuel. Eat more.
If Severe Muscle Soreness Lasts 5+ Days
You overdid it. Take 2-3 rest days. Increase protein to 150g daily. Next workout: 50% intensity. Build back slowly.
If Scale Stops Moving But Measurements Decrease
Normal. You're losing fat, gaining muscle from exercise. Scale doesn't show this. Waist circumference is better metric. This is actually better body composition.
If Injured During Workout
Stop that exercise. Rest 3-5 days. Do other muscle groups. Weight loss doesn't stop just because you can't train one area.
Performance Expectations Timeline
- Week 1-4: Weak, tired. That's ok. Building foundation.
- Week 5-8: Strength improving. Energy up. Endurance building.
- Week 9-16: Noticeable strength gains. Can lift heavier. Faster/longer cardio. Weight dropping 1.2-1.5kg/week.
- Week 17+: Performance-athlete phase. Aesthetic changes obvious. Energy high. Sustainable long-term.
When to Seek Help
Contact a trainer if:
- Unsure about proper form on lifts
- Not seeing strength progress after 4 weeks consistent training
- Persistent pain in joints (not muscle soreness)
- Want custom program designed for your goals
EkoPeptide can recommend Lagos personal trainers experienced with GLP-1 clients (different approach than normal training).
Related Articles:
Nutrition Guide for Weight Loss Tracking Exercise Performance Side Effects Management During ExerciseLagos trainers create GLP-1-optimized programs • Pair with nutrition + medical oversight
References
Medically Reviewed by Dr. Chukwuemeka Okonkwo
MBBS, FMCP - Endocrinology
Content reviewed by qualified healthcare professionals for accuracy.