GLP-1 Injection Sites

Approved Injection Sites

GLP-1 medications are subcutaneous injections—they go into the fatty tissue just under the skin. Three areas are approved:

Why Site Rotation Matters

Injecting in the same exact spot repeatedly can cause:

• Lipodystrophy: Changes in fat tissue—lumps or dips at injection sites
• Reduced absorption: Scar tissue can affect how medication is absorbed
• Increased discomfort: Overused areas become more sensitive

Which Site Works Best?

Absorption is equivalent across all three sites, so choose based on comfort and convenience:

Choose abdomen if: You want the easiest access, typically lowest discomfort, and most tissue to work with. Most users prefer this site.

Choose thigh if: You prefer not to lift clothing, want to inject while sitting, or need another option for rotation.

Choose arm if: You have someone to help, prefer it out of sight, or find it most comfortable for your body type.

Areas to Avoid

• Within 2 inches of the belly button
• Areas with bruises, cuts, or skin irritation
• Scar tissue
• Stretch marks (reduced absorption possible)
• Areas with prominent veins
• The same exact spot as previous weeks

Tips for Lagos Users

A few practical considerations for our climate:

• Sweat: Make sure the injection site is clean and dry. Wipe with alcohol and let it dry completely.
• Clothing: Abdomen works well when you need to inject discreetly without fully undressing.
• Travel: If moving around Lagos, thigh injections work well when you need to inject in transit (car, office bathroom).